Calcitonin's effect on calcium homeostasis primarily involves which tissue?

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Multiple Choice

Calcitonin's effect on calcium homeostasis primarily involves which tissue?

Explanation:
Calcitonin’s primary action is on bone. It is released when calcium levels are high and directly inhibits osteoclasts, the cells that break down bone and release calcium into the blood. By reducing bone resorption, calcium remains stored in bone rather than entering the bloodstream, making bone the main tissue involved in its calcium-regulating effect. Muscle and liver aren’t the primary targets, and the kidney’s role is secondary and less central, though there can be some renal calcium handling changes. Overall, calcitonin works to lower serum calcium by limiting bone breakdown.

Calcitonin’s primary action is on bone. It is released when calcium levels are high and directly inhibits osteoclasts, the cells that break down bone and release calcium into the blood. By reducing bone resorption, calcium remains stored in bone rather than entering the bloodstream, making bone the main tissue involved in its calcium-regulating effect. Muscle and liver aren’t the primary targets, and the kidney’s role is secondary and less central, though there can be some renal calcium handling changes. Overall, calcitonin works to lower serum calcium by limiting bone breakdown.

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