What is metformin's primary action in type 2 diabetes?

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Study for the NCLEX with quiz on the Endocrine System. Engage with multiple choice questions, detailed explanations, and tips for success. Prepare for your NCLEX exam!

Multiple Choice

What is metformin's primary action in type 2 diabetes?

Explanation:
Metformin works mainly by lowering glucose produced by the liver and by making body tissues more responsive to insulin. By dampening hepatic gluconeogenesis and enhancing insulin sensitivity in muscle and other tissues, it helps reduce both fasting and post-meal glucose levels. It does not primarily stimulate the pancreas to secrete more insulin, and its main effect isn’t to block intestinal glucose absorption. So, the best description is that metformin decreases hepatic glucose production and increases insulin sensitivity, leading to better overall glucose control.

Metformin works mainly by lowering glucose produced by the liver and by making body tissues more responsive to insulin. By dampening hepatic gluconeogenesis and enhancing insulin sensitivity in muscle and other tissues, it helps reduce both fasting and post-meal glucose levels. It does not primarily stimulate the pancreas to secrete more insulin, and its main effect isn’t to block intestinal glucose absorption. So, the best description is that metformin decreases hepatic glucose production and increases insulin sensitivity, leading to better overall glucose control.

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