Which statement best describes the laboratory pattern in autoimmune hypothyroidism?

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Study for the NCLEX with quiz on the Endocrine System. Engage with multiple choice questions, detailed explanations, and tips for success. Prepare for your NCLEX exam!

Multiple Choice

Which statement best describes the laboratory pattern in autoimmune hypothyroidism?

Explanation:
Autoimmune hypothyroidism is a primary thyroid failure. The thyroid can’t produce enough hormones, so circulating levels of free T4 (and often T3) fall. In response, the pituitary raises TSH in an attempt to stimulate the thyroid. The typical lab picture is an elevated TSH with a low free T4 (and sometimes low T3 as the disease progresses). If TSH is normal with normal T4, that indicates euthyroid function, not autoimmune hypothyroidism.

Autoimmune hypothyroidism is a primary thyroid failure. The thyroid can’t produce enough hormones, so circulating levels of free T4 (and often T3) fall. In response, the pituitary raises TSH in an attempt to stimulate the thyroid. The typical lab picture is an elevated TSH with a low free T4 (and sometimes low T3 as the disease progresses). If TSH is normal with normal T4, that indicates euthyroid function, not autoimmune hypothyroidism.

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